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What is the Real Importance of Bioavailability When It Pertains to CBD?

When shopping for CBD, you need to make a point of choosing a product that comes from a trusted company. Not only that, but you should also look for lab reports that prove the quality, choose a method of delivery that works for you, and make sure the milligram strength is right for your needs. However, there’s an equally important consideration that is frequently overlooked, mainly because it is a bit more abstract than the others. Bioavailability can make or break a CBD product’s ability to help you reach your goals. Hence, there are several things that can determine how bioavailable a particular CBD product actually is.

Now, for those of you who are confused about what bioavailability is, how it works, and why it’s crucial , allow us to clear things up for you.

What is Bioavailability?

Bioavailability refers to how capable a compound is of absorbing into the body.  In terms of CBD, bioavailability reflects how easily the compounds in hemp absorb so that the body can fully utilize them.  The more bioavailable a CBD product is, the higher the amount of hemp extract’s chemical composition reaches those desired areas. From there, they will then become active and produce effects.  You would be surprised by how much this single factor determines how successful your CBD experience is overall.

As you will also see, there is no method for measuring bioavailability.  In simple terms, it is too complex of a concept.  That’s why you need to simply know what to look for in a product to determine its bioavailability potential.

What Factors Determine the Bioavailability of a CBD Product?

When we hear others out there discuss the “best” way to take or apply cannabidiol, it almost always hits on the topic of bioavailability. So, with that said, let’s break down the different factors that determine a CBD product’s bioavailability level.

Factor #1: How the CBD Was Extracted

One big factor is the extraction method that was used to develop a hemp extract from the plant material. There are a few different methods out there, but the CO2 method is by far the best one. This method preserves bioavailability by gently lifting the desired compounds without damaging their structural integrity or stability. The result is a product that absorbs into the body at an easier pace.

Factor #2: The Type of Hemp Extract Used

There are three types of hemp extract:

  • CBD Isolate: Pure CBD without any other compounds, as they have been removed from the final product. 
  • Full Spectrum: Contains every desirable compound in hemp, including cannabinoids, terpenes, etc. 
  • Broad Spectrum: Like full spectrum, it too has every compound in hemp with the exception of Tetrahydrocannabinol (THC). That has been chemically removed.

Full spectrum CBD is the most likely to offer maximum bioavailability because of synergy. When all of the compounds are consumed at once, as nature intended, the entourage effect occurs. This boosts bioavailability throughout the entire chemical composition.

Factor #3: A CBD Product’s Milligram Strength

The more milligrams you consume in one dose, the more bioavailable the product is.  How?  Because higher concentrations greatly increase your ability to absorb as much of the compounds as you possibly can, to put it simply.

Factor #4: Delivery Method

Each delivery method has its own bioavailability level as well. 

  • Edibles are mid-bioavailable because of how they are digested and processed by the liver. 
  • Tinctures can be highly bioavailable because they absorb directly into the tissue where the product was administered, ensuring more efficient absorption into the body.

Factor #5: How the CBD Product Was Formulated

How the product was formulated makes a difference. For one thing, some additional ingredients may interfere with bioavailability by causing the compounds in hemp to become less stable. Furthermore, some companies use advanced nanotechnological methods to change the cannabidiol on a molecular level, making it more easily absorbed into the body.

Lab testing of CBD

#6: When the CBD Product was Produced

Another factor that’s often overlooked is how old the product is. The fresher the product, the higher its bioavailability level. This applies to all kinds of products, including medications, which are known to lose their potency as they sit around in the medicine cabinet. CBD is an organic substance that will slowly break down the longer you hold onto it.  Therefore, always aim to buy hemp-based products that were made as recently as possible and try to use them up before they reach their expiration date.

Overall, You Cannot Really Increase the Bioavailability of CBD

Optimizing your method of administration (sublingually or topically) to ensure you receive your ideal dose of cannabidiol is going to be key.  Simply buy the highest-quality CBD product at the highest milligram strength that’s available.  However, if something is interfering with its bioavailability, you will not reap the full benefits that hemp can offer.

One other tip, when consuming or applying a CBD product at home, work, or wherever, attempt to multiply the bioavailability rate by the amount of CBD in a serving size.  This will help you get a better gauge of what that dosage is that you’re looking for.

By understanding bioavailability and what factors determine it, you can apply this information to your future hemp shopping sessions at Pure CBD Now for better results overall. Here are some CBD products that you can check out:

Taking a drop of CBD


  1. https://www.leafly.com/news/cannabis-101/what-are-co2-marijuana-concentrates
  2. https://weedmaps.com/learn/dictionary/terpenes
  3. https://www.livescience.com/24553-what-is-thc.html
  4. https://weedmaps.com/learn/dictionary/synergy
  5. https://www.cannabistech.com/articles/what-is-the-entourage-effect-in-cannabis/
  6. https://dailycbd.com/en/nano-cbd/

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